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NFL Week 4 Preview: Who to Trust, Who’s Sliding & Key Matchups in the Week 4 NFL Schedule

As the 2025 NFL season rolls into NFL Week 4, teams that began with promise will be tested, while others will seek redemption. With many clubs already 3-0, the stakes are rising and the week 4 nfl schedule features matchups that could alter playoff trajectories. From MVP races heating up to surprising trends, here’s everything to watch for as we head into Week 4.

Teams Rising, Teams Falling

There are several undefeated squads catching eyes as Week 4 begins. The Philadelphia Eagles, after overcoming a 19-point deficit to down the Rams in dramatic fashion and recovering two blocked field goals, are proving they can win ugly as well as stylish.

The Indianapolis Colts are also drawing attention, mostly thanks to Daniel Jones, who has posted three passing touchdowns, three rushing touchdowns, and zero turnovers through three games. That performance has many wondering if Daniel Jones has entered the MVP conversation.

On the opposite end, the San Francisco 49ers are showing cracks despite their 3-0 record. Injuries are piling up—quarterback Brock Purdy, tight end George Kittle, and wideouts Jauan Jennings and Brandon Aiyuk have all missed time. Backup Mac Jones has stepped in admirably, but questions remain about depth and sustainability.

What to Watch in the Week 4 NFL Schedule

The week 4 nfl schedule presents some marquee games, including:

  • Baltimore Ravens vs. Kansas City Chiefs — Two franchises each with something to prove. The Ravens are aiming to overcome past struggles against Mahomes-led squads, while the Chiefs can’t afford to slip to 1-3 as they try to defend the AFC West.
  • Eagles vs. Buccaneers — A pivotal showdown, especially as the Buccaneers carry several key injuries into this stretch.

These matchups are likely to be critical turning points for several teams, depending on how Week 4 unfolds.

MVP Watch & Emerging Players

Daniel Jones might be the breakout name of the season. Given the Colts’ hot start, he’s being discussed among playoff contenders and MVP hopefuls. The week 4 nfl schedule pits his team in games where sharp performances could further elevate his profile.

Other names rising include Justin Herbert and Josh Allen, who continue to make MVP cases with strong starts — Allen with the Bills’ elite offense, Herbert with the Chargers’ revived passing attack.

Potential Risks & What to Sell

Despite 3-0 records, some teams may not be what they seem under close inspection:

  • The 49ers may be overvalued. Without their key offensive weapons, there’s reason for concern that they won’t hold up against stronger competition in the week 4 nfl schedule and beyond.
  • The Buccaneers are winning close games but are stretched thin by injuries. Their upcoming stretch of games could expose roster weaknesses.

Trends to Note

  • Special teams have made major contributions — blocked field goals, game-sealing kicks, and returns have swung momentum.
  • Defenses, especially for teams like Cleveland and the Colts, are showing adaptability—and turning turnovers into wins.
  • Offensively, balancing run and pass remains key. Teams leaning too heavily on one side are being slated as easier to shut down by more versatile opponents.

Looking Ahead

As NFL Week 4 gets underway, the week 4 nfl schedule is loaded with must-watch games. The outcomes will influence MVP debates, playoff seeding, and which teams are legitimate contenders versus pretenders. Keep eyes on matchups involving Philadelphia, Indianapolis, Kansas City, and Baltimore.

Will Daniel Jones continue his surge? Can injured clubs overcome adversity? Is there a team ready to crash the ranks of the undefeated? Week 4 promises answers.

For more breaking NFL stories, previews, and in-depth analysis, stay updated through all your favorite sports sources. Want startup news, technology, business, and more in one place? Check out Startup News for the latest.

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