A I-designed compounds can kill drug-resistant bacteria

The top candidates they discovered are structurally distinct from any existing antibiotics, and they appear to work by novel mechanisms that disrupt bacterial cell membranes. This makes them less vulnerable to antibiotic resistance, a growing problem: It is estimated that drug-­resistant bacterial infections cause nearly 5 million deaths per year worldwide.

Now that they can generate and evaluate compounds that have never been seen before, the researchers hope they can use the same strategy to…